Sentence examples for clones which may from inspiring English sources
Due to the skewed frequency distribution of T-cell clones, the small fraction of highly expanded T-cell clones, which may dominate the TCR repertoires, require further exploration.
Moreover, the results showed that lesion antigen-associated T-cell clones were generated and accumulated with tumour progression and became highly expanded T-cell clones, which may play a key role in tumour immunity.
This might be related to the level of expression of the protein in the clones, which may not be high enough and, above all, to its stable expression.
Our in vitro technique involves culture of fresh isolates in the field ("ex-vivo") to mitigate losing clones, perhaps artemisinin resistant clones, which may not survive cryopreservation.
Amplified phage populations serve for additional selection round(s) and allow enrichment of selective clones, which may be determined by comparing unselected to selected libraries through DNA sequencing [1] [4].
We have demonstrated that MLST, as a nucleotide sequenced-based strain typing method, has the power to bring life to a microbial metagenome by the identification of matching cultivable clones, which may now be used as viable surrogates for research using the metagenome.
When multiple clones are present in a tumor, molecular assays reflect an average signal of the population, or, alternatively, only the signal from the dominant clone, which may not be the most malignant clone present in the tumor.
The capacity to form metastases may be confined to a particular cellular clone, which may during the progression of the disease result in heterogeneity between the primary and metastases.
With pleomorphic adenoma it is widely accepted that both epithelial and mesenchymal (myxoid, hyaline, chondroid, osseous) elements often arise from the same cell clone, which may be a myoepithelial or ductal reserve cell [ 19, 20].
Additionally, there is evidence suggesting that MDS may start with multiple minor clones [6], which may be missed with conventional cytogenetic studies at the initial presentation.
Given the potential for cloning errors, which may result in recombinant alleles, singleton mutations, as well as non-target DNA incorporation during cloning [33], conservative criteria were used to confirm the presence of alleles.
