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These losses of clones were caused by the prolonged period (approx. 82 generations) of culture under suboptimal stock conditions following isolation of the lineages.
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The 3 serogroup A pandemic waves reaching the African meningitis belt were caused by clones of subgroup III (11, 12 ), and the recent outbreaks of W135 in West Africa were caused by strains belonging to the ET-37 complex (3, 13 ).
These clusters were caused by different clones, involved mostly children, and were accompanied by high case-fatality rates.
To elaborate on the origin of the mwh clones in wings of the w/mwh+ Y; mwh males after formaldehyde treatment, we analyzed 20 wings of w /Y; VK16 mwh+/ In 2LR Gla ; mwh males in which the mwh clones cannot be caused by chromosome loss or recombination.
Xing et al. [ 59] recently demonstrated that reduced developmental potential of pig embryos generated by multiple rounds of cloning was associated with altered gene expression patterns, and a previous report stated that the reduction of cloning efficiency with additional rounds of cloning may be caused by accumulation of epigenetic errors [ 60].
The decrease in the abundance of common clones could also be caused by selection pressure acting in a negative frequency-dependent manner.
Her death seems unconnected to the fact that she was a clone; the tumor is caused by a virus that had infected both cloned and normal sheep at the institute.
We also demonstrate that the emergence of the Hajj clone in 2000 was caused by a meningococcal strain that was distinct from other circulating serogroup W ST-11 strains.
This implies that the boundary effects seen in clones of capsDel1 trn28.4 cells are caused by the juxtaposition of cells expressing Caps and Trn with cells not expressing them.
A dip occurs when beneficial alleles in a successful clone remove the ancestral sequence diversity in competing clones; the subsequent rebound of diversity is caused by new mutations within the successful clone.
Redundancy is caused by clones obtained by cDNA subtraction and representing different portions of the same or highly similar genes, and also by duplicates spotted from both A. thaliana and B. divaricarpa.
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