Sentence examples for clones to activate from inspiring English sources

Thus, we examined the ability of SF CM from the Bowes melanoma clones to activate HDFs, and whether PLX4032 could attenuate this activation.

During T cell activation, anergic clones fail to activate ERK1/2; however, there is also evidence that inhibition of ERK1/2 alone cannot act on this unresponsive state known as clonal anergy [ 47].

B22a1 could also stimulate the 3D4-1.2 3D4-1.2t high clonentration but failed to activate CII-specific clones not expressing thighα16/Vβ12 Tconcentrationn.

ASP13 clone showed an increased capacity to activate Raf that was associated with increased pERK levels, while no differences were observed on PI3K cascade measured by pAKT levels.

In contrast, αGC as a free drug was unable to activate iNKT cell clones in the absence of APCs (Fig.  2a) and required the presence of CD1d-expressing cells such as the human lymphoma C1R transfected with CD1d (Fig.  2b).

In the immune system, for instance, degeneracy of antigen receptors enables any single epitope to activate many different lymphocyte clones, and simultaneously any single lymphocyte clone is able to recognize many different epitopes [ 23].

One approach often employed to identify the peptides recognized by such CTL is expression cloning, which consists in isolating the peptide-encoding gene by transfecting a library of tumoral cDNA and testing the transfected cells for their ability to activate the CTL clone [ 13, 14].

As suggested by the expansion of human iNKT cells, αGC-loaded sCD1d proteins did not require the presence of APCs and were sufficient to activate human iNKT cell clones to release IFNγ after 18-h incubation (Fig.  2a).

Some of the toxins produced by S. aureus are called superantigens (SAgs) because they are endowed with the ability to activate various T cell clones, independently of their specificity.

Attempts to activate this BES in two independent clones were unsuccessful, suggesting that this mini-BES may not be functional.

In general, clones that showed a high degree of repression were more difficult to activate and vice versa.