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Clone detectability was around 0.6 in sample pairs collected 24 hours apart [31].
The relationship of clone detectability with age, MOI and parasite density was determined.
Quantification of clone detectability at any time point of blood sampling contributes relevant information on the reliability of PCR corrections.
Furthermore, the number of newly acquired clones per time interval might be a suitable outcome measurement of antimalarial interventions; the parameter "clone detectability" might also correct this estimate.
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Detectability,
These are major differences between both species, but with respect to detectability of parasite clones in the blood stream, both species differ less than previously thought.
Daily fluctuations in detectability of P. Vivax clones have not yet been investigated.
Despite this biological difference, the detectability of individual parasite clones was lower in P. vivax than in P. falciparum.
This study aimed at measuring the detectability of individual P. falciparum and P. vivax parasite clones in consecutive samples of the same patient and at investigating the impact of sampling strategies on basic epidemiological measures such as multiplicity of infection (MOI).
However, our observation that detectability decreased with increasing MOI, suggests impaired amplification of minority clones.
"It was below the level of detectability, but there can still be some leukemia cells present".
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CEO of Professional Science Editing for Scientists @ prosciediting.com