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Conversely, clonal elimination of Gαs leads to autonomous prevention of the cell death.
Clonal elimination of Gαs results in failure of the cell death in the wing [22].
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The elimination round features tag team sushi.
†Stepwise backward elimination.
The antibody network model as well as the evolution process including clonal proliferation, immune elimination, and immune memory is studied.
This reduces differences in selection pressure on different clonal genotypes and slows elimination of individual allele species.
The advantage of this isogenic system is the elimination of clonal variation in cell growth/death rates and phenotypic drift that can occur in stable cell line models.
Even among those sterile mutations destined for elimination by clonal interference, there is substantial variation in their overall success, as measured by the maximum frequency they attain in the population, %max.
The presented mechanistic approach is embedded in the classical framework of a multistage and evolutionary cancer model where individual somatic cancer evolution starts with one cell and proceeds with successive rounds of mutation acquisitions, clonal expansions and partial elimination of tumor subclones by various mechanisms (Beckman and Loeb, 2005a).
Clinical data have demonstrated that lenalidomide often has a potent myeloablative effect during the early stages of treatment which coincides with the effective elimination of del 5q) clonal myeloid progenitors [ 9].
Where the L-genome is eliminated and the R-genome transmitted, P. esculentus occur in sympatry and mate with the parental species P. lessonae (LE-system); where the reverse pattern exists (elimination of R, clonal transmission of L), hybrids co-occur and mate with P. ridibundus (RE-system) [ 30].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com