The horizontal mobility of the NDM-1 gene involving different plasmids play a major role in the dissemination of this resistance determinant but clonal spread and involvement of the globally disseminated ST258 Klebsiella pneumoniae lineage has also been reported [9], [11].
Analogous to ST131 among ESBL-EC, several widely disseminated clonal groups of ESBL-producing K. pneumoniae (ESBL-KP) have also been identified, including K. pneumoniae ST11, ST15, ST16, ST23, and ST48 [ 8- 12].
These outcomes illustrate the clonal enrichment of a select genetically modified, highly malignant sub-population disseminating to distant sites and promoting aggressive disease.
Among the various GAS serotypes, the globally disseminated M1T1 clonal strain remains the most frequently isolated from cases of invasive and non-invasive infections [2], [3], and although disease severity partially depends on host genetic factors [4], [5], [6], M1T1 GAS possesses unique genomic features that contribute to its evolutionary fitness [7], [8], [9], [10].
Resistance may be disseminated through clonal expansion of drug-resistant strains or through horizontal transfer of genetic elements coding for resistance determinants.
These integrons are still mobilizable (28 ) but chromosomal location may make them more likely to be disseminated through clonal expansion than through horizontal gene transfer, particularly in the absence of antimicrobial selective pressure.
The clouds are disseminating.
And Google is disseminating it.
or "disseminating fake news"?
Instead of disseminating, each relay has to disseminate (16).
