Over 50% of both clonal groups displayed high-level resistance to mupirocin.
All clonal pairs displayed concordant ER-positivity between paired lesions, yet the subsequent lesions were not restricted to low-grade disease.
The observation that all cells were positive for one of the markers in a marker cocktail (CD14, CD20, CD34 and CD45) (data not shown) supports the argument that neither clonal subtype displayed pure MSC properties.
Some of these clonal complexes display host preference.
In mouse model, CF clonal strains, displaying a mucoid and a non-mucoid phenotype, showed a similar capacity of persistence [ 17].
Typhimurium 135@ isolates formed a tight clonal group, displaying ≤23 SNPs between pairs of isolates (red branches in Figures 1, 2).
In the blood, CD8+ T cells with clonal expansions display a memory phenotype, biased toward the CM and TEMRA phenotype with an overexpression of CCR5 and CD11a.
Thus the Barrett's cells transformed in vitro displayed clonal chromosomal abnormalities consistent with neoplasia.
However, though less diverse, all these populations were far from being clonal and none displayed extreme reductions in genetic variation such as those reported for other invasive phytopathogenic fungi (e.g., P. infestans [84], P. ramorum [27], Sphaeropsis sapinea [85], U. scitaminea [82], Magnaporthe grisea [33], Ceratocystis fimbriata f. platani [26], Fusarium circinatum [86]).
Of the two children treated in Zurich, one developed MDS while the other displayed clonal expansion without MDS.
