Exact(6)
A slow molecular clock suggests that the time between generations is long, something that has historically set humans apart from the great apes.
A recent model of the circadian clock suggests that outputs of the clock which also feed back into it, can strengthen rhythms.
The transcriptional signature of the molecular clock suggests that the basal level of output genes that show a circadian rhythm of expression may be up-regulated at the onset of lactation, particularly in the mammary gland.
A molecular clock suggests that the diversification of Coccinia began about 6.9 Ma ago, with most of the extant species diversity dating to the Pliocene.
The null hypothesis of a molecular clock suggests that the number of nucleotide substitutions between two lineages would be the same.
Although only 22 30% of cycling mRNA is driven transcriptionally (Koike et al., 2012; Menet et al., 2012), demonstration of involvement of the nuclear envelope in regulation of the molecular circadian clock suggests one pathway through which the nuclear envelope may globally and temporally regulate large numbers of genes.
Similar(54)
Nonetheless, conversations about the biological clock suggested that reproduction was an exclusively female concern.
Sleep loss also had a dramatic effect on genes that govern the body's biological clock, suggesting that poor sleep might trigger a vicious cycle of worsening sleep disruption.
At one end, Yevgenia Nayberg, the production designer, has installed a whitewashed expanse of drywall sparsely flocked with items from Faith's life -- like a pyramid of Campbell's cans for the soup kitchen and a clock suggesting the ticking away of her childbearing years -- that represents the unfinished, practically empty nature of the heroine's existence.
Although Garcia et al. showed that NPAS2 is not expressed in the SCN [21], DeBruyne et al. demonstrated that wheel-running running behavior is rhythmic when the Clock gene is nonfunctional, but arrhythmic in mice deficient in both NPAS2 and CLOCK, suggesting that NPAS2 is expressed in the SCN and is functionally redundant with CLOCK [27].
Estimates of rate variation derived from empirical data in plethodontid salamanders were less than those derived from comparable datasets simulated under an enforced molecular clock, suggesting that the empirically-estimated rate variation may reflect error rather than true differences in the underlying biological substitution process.
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