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Open image in new window Fig. 18 SIMUL8 clock properties.
We ascribed their behavior to alterations in other clock properties like amplitude [13].
We have shown previously that for individuals of extreme chronotype ("larks" and "owls"), clock properties measured in human fibroblasts correlated with extreme diurnal behavior.
In each trial, the correlations that we observed suggested that this easy cellular method could be used as a biomarker for human clock properties.
Interestingly, although blind individuals showed on average the same fibroblast clock properties as sighted ones, their physiological periods were significantly longer.
We conclude that the period of human circadian behaviour is mostly driven by cellular clock properties in normal individuals and can be approximated by measurement in peripheral cells such as fibroblasts.
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However, the same reference clock property introduces a new challenge for the design of joint carrier and sampling clock synchronization, where the frequency offsets have relationship with the sampling frequency offset besides the Doppler shift.
By retaining the acket transmission order, LE measures the exact number of lost packets upon a single duplicate ACK, making it possible to strictly extend the self clocking property.
The circadian clock uses properties of both self-sustained oscillation and sensitivity to environmental light for its resetting.
Indeed, the mismatch between upper and lower teeth of different species is so phylogenetically scaled that it has almost clock-like properties [ 7].
The statistical guarantees for SVDquartets requires a strict molecular clock, a property that is not likely to hold on most biological datasets, especially when the species are not very closely related, and when loci are sampled from throughout the genomes.
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