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Although this is the standard method, it is imprecise, Dr. O'Brien said, adding that this molecular clock method could be off by hundreds of years.
We estimated divergence times using the Bayesian relaxed clock method calibrated with node ages from previous studies.
To verify their results, the researchers turned to the molecular clock method, which assumes a constant rate of genetic mutation to date a species.
Next was Różycki's "clock" method, which sometimes made it possible to determine which rotor was at the right-hand side of the Enigma machine on a given day.
Divergence times were estimated using the uncorrelated relaxed clock method [45] as implemented in BEAST v.1.5.2 [46].
Secondly, we used a relaxed (uncorrelated lognormal) molecular clock method [68] as implemented in BEAST version 1.4.6 [69].
A relaxed molecular clock method allowing autocorrelated rates of evolution along branches [64] was also implemented here.
Molecular divergence dates were calculated using the 20.1 kb molecular supermatrix of Beck [10] and the Bayesian relaxed molecular clock method implemented in BEAST 1.4 [26].
Using a relaxed clock method on the Atyid 16S dataset, the time to most recent common ancestor for S. lancifera/stylifera/sp.
Second, Bayesian estimates of evolutionary rates along the genealogy of M. graminicola were calculated using the "relaxed clock method" [34] from values obtained with the genetic coalescent analysis described above.
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Recently, a Bayesian relaxed-clock method that allows the implementation of sophisticated calibration methods has been published [21].
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