Sentence examples for clock factors from inspiring English sources
Our work reveals a specified function for local clock factors in histaminergic circuitry controlling arousal.
To test this, first, we explored how KPNB1 knockdown affects cellular localization of the core clock factors.
Future studies will likely identify more interactions between circadian clock factors and nuclear receptors to expose the full extent of their physical relationship.
The dosage dependent effect of the short 2-minute light pulse on feeding propensity over time suggests it may represent a masking effect which however involves several clock factors.
Hes7 is known to act as one of the core molecular clock factors during somite formation in developing mouse embryos, generating 2 h-period oscillations with fast (i.e. a half-life of about 20 min) mRNA and protein turnover rates (Bessho et al., 2001, 2003).
Seven of these genes (tim, putative to1, to 2, to3, obp4, obp22, and obp26) were selected on the basis of their expression patterns (Additional file 5), and the remaining three (per, clk1 and cry) were included as representative of previously identified circadian clock factors.
46 This previously unforeseen activity of a core clock factor has several, far-reaching biological implications.
As a further analysis of circadian function, we tested whether any Eurydice clock factor might rescue circadian activity rhythms in null mutant Drosophila.
Therefore, the studies of LL and Epper RNA knockdown give similar conclusions: compromise of circadian timing by disrupting light input or by knockdown of a canonical clock factor had no effect on tidal periodicity.
The ticking-clock factor in "K-19" plays to her strengths.Unnatural though it may seem, the notion of gliding, silent, unseen and underwater, has had a magnetic pull since before submarines were invented.
These analyses revealed different effects of the factors on clock and light-regulated promoter activation, demonstrating various mechanisms by which light-induced transcription factors modulate clock gene expression and thereby transmit photic information to the core clock.
