Sentence examples for clock elements from inspiring English sources

ARNTL and CLOCK gene products make up core clock elements that generate circadian rhythms.

Furthermore, conditional knockdown of Tim in the rat suprachiasmatic nucleus disrupted the rhythms of neuronal activity and altered levels of clock elements, suggesting a role similar to that of its Drosophila counterpart [18].

Indeed, the observed period effects are comparable to or even greater than those when overexpressing per, tim or Clk, suggesting that perturbation of cell membrane recycling may be as important as these canonical core clock elements to period determination [47], 65. shits1 effects are modulated by components of endocytic pathways.

Similar approaches have been used to characterize conserved clock elements in several plant species.

Since both circadian rhythms and photoperiodism rely upon daily cycles of environmental change, it seems reasonable to assume that the same clock elements are involved in both processes.

These results indicate that following the 5 9 somites stage of development, the expression of key core clock elements becomes responsive to temperature changes.

Our observation suggested that none of these factors are the predicted clock element, and thus alternative approaches must be used to define such circadian mutants.

In mammals, the central clock component CLOCK is a histone acetyltranferase that binds in a multiprotein complex to promoters containing E-box DNA elements [ 28].

It was infused with a beat-the-clock element: his illness coincided with the debate over health care ("the cause of my life") and the election of a young president he championed.

These promoter sequences are considered to be definitive clock regulatory elements [ 91, 94, 95].

gambiae to explain our results that consists of: i) separate clock response element(s) or 'clock box' (CB) and light response element(s) or 'light box' (LB) within the promoters of rhythmic genes; and/or ii) the action of light signaling impinging upon pathways upstream of the CB but downstream of the TTFL.