Sentence examples for clock component from inspiring English sources

In mammals, the central clock component CLOCK is a histone acetyltranferase that binds in a multiprotein complex to promoters containing E-box DNA elements [ 28].

Cryptochrome 1 (Cry1), an essential clock component, displays evening-time expression and serves as a strong repressor at morning-time elements (E box/E′ box).

We tested the function of the light-responsive circadian clock in the vvd mutant and found no major defect in the circadian rhythm of conidiation or light regulation of a key clock component, frequency (frq).

The biology or cause for NES is not clear, but it is thought that there may be a circadian or body clock component.

AMPK also regulates circadian rhythm by phosphorylating the clock component CRY1 and decreasing its stability [39].

Surprisingly, Cry1, a clock component not inducible by light in mammals, became slightly inducible in these mice.

The importance of a clock component can be inferred by the magnitude of its phenotype when perturbed.

Clock components are "obviously much larger and therefore slightly less complicated to manufacture and to assemble," said Karl-Friedrich Scheufele, co-president of Chopard.

Whether molecular clock components are good indicators for SCN aging remain unclear.

Forward genetic approaches (phenotype to gene) are powerful methods to identify mouse circadian clock components.

They can search for other clock components by looking for proteins CLOCK interacts with and genes that it activates.