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Masri, S. & Sassone-Corsi, P. The circadian clock: a framework linking metabolism, epigenetics and neuronal function.
In this framework, an increase in arousal caused by the appearance of an oddball stimulus leads to a transient increase in the internal clock's tick rate.
Within an internal clock framework, a change in attentional resources can produce longer perceived durations.
We estimated phylogeographical structuring and divergence dates independently for each locus using a relaxed Bayesian molecular clock framework implemented in BEAST v1.7.4 [ 41].
In contrast, in a Bayesian relaxed-clock framework, all divergence dates are estimated from the primary sequence data.
A dating analysis is run using an uncorrelated relaxed molecular clock model within a Bayesian framework with direct fossil calibrations.
What's the framework?
In order to investigate the role of positive regulators of the somitogenesis clock, we modified previous frameworks to account for the role of NICD in the somitogenesis clock.
In "Results and discussion" section, we evaluate the framework's methods in terms of wall-clock completion time and scalability.
We present a detailed experimental and comparative evaluation with similar approaches and exhibit our framework's efficiency in terms of scalability and wall-clock completion time.
The estimation of the number of clocks in a standard likelihood framework is not easy, as the models are generally not nested and are typically derived from the data.
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