Sentence examples for clip sequence from inspiring English sources

To this end, a construct encoding the invariant chain (Ii) was engineered in which the Class II associated invariant chain peptide (CLIP) sequence was replaced by an immunogenic epitope derived form Heat Shock Protein 60, HSP60 178–186.

On Sunday, Dick Cavett took the stage at Guild Hall with a younger fellow Yale graduate, Eric Metaxas, after a clip sequence of his state-of-the-art shows featuring Bette Davis, Groucho Marx, Fred Astaire, Jack Benny, Mel Brooks, Woody Allen, etc. Spry and charming Cavett spoke about his youth in Lincoln, Nebraska, the first time he got the fame bug at age 10.

This loop contains the CLIP sequence, which fills the cleft of the MHCII heterodimer [6].

The subunits were placed manually avoiding steric overlap and allowing insertion of missing loop segments between the C-terminal trimerisation domain, the CLIP sequence and the N-terminal coiled-coil structure employing the loop builder option in SPDBViewer.

We postulate that upon binding of a single MHCII heterodimer to one unstructured CLIP sequence, the triple-helical core domain of Ii3 changes its conformation, which imposes a steric constraint onto the entire complex, discouraging binding of further MHCII heterodimers.

In the model, the binding of the CLIP sequence to the MHCII heterodimer is sterically possible in the complex if one assumes a slightly kinked arrangement of the MHCII molecule with respect to the membrane.

In this case, the extracted soft clip contains untemplated sequence and when re-aligned to the reference, the re-aligned soft clip sequences will themselves be soft-clipped (by Θ nt).

Clip sequences that did not imply causality may have activated an error-detection mechanism and triggered event boundary perception processes.

We thus present a pentamer model where only one single DR, DQ, or DP heterodimer is contained in a MHCII-Ii complex and propose a conformational change induced upon binding of one MHCII heterodimer to the Ii3 that could explain why class II molecules do not abundantly occupy all three CLIP sequences contained in the Ii3 complex.

Preprocessing produces a FASTQ file of long soft clip sequences and a BAM file of reads with short soft clips.

Matching short soft clips: Short soft clip sequences are used to try to find reciprocal support for the remaining unpaired clusters by directly searching the cluster anchor region using short soft clip sequences derived from the re-aligned locus.