Sentence examples for clinically targeted from inspiring English sources

Genetic and pharmacologic suppression of branched-chain alpha-ketoacid dehydrogenase kinase, a clinically targeted regulatory kinase, induces BCAA oxidation primarily in skeletal muscle of healthy mice.

To test whether the use of an evidence retrieval system that uses clinically targeted meta-search filters can enhance the rate at which clinicians make correct decisions, reduce the effort involved in locating evidence, and provide an intuitive match between clinical tasks and search filters.

Which cells should be clinically targeted for the treatment of NP degeneration therefore remains unclear.

CTLA-4 was the first negative regulatory checkpoint receptor to be clinically targeted.

V100 and D90 should be over 95%andd 144Gy respectively for the clinically targeted volume [ 11, 12].

This suggests the appropriateness of programs at all levels (national and clinically targeted) designed to reduce perceived stigma, including those publicising the actual levels of personal stigma.

While most therapeutics used clinically target proteins, RNA research is revealing a wealth of potential RNA targets, including splice sites.

The strategy of clinically targeting cancerous cells at their most vulnerable state during mitosis has instigated numerous studies into the mitotic cell death (MCD) pathway.

This is attributable to the low bioavailability of statins in bone, as all of the current statins used clinically target the liver.

Clinically, target occupancy can be used to unequivocally confirm "drug-on-target" (proof of mechanism), (Morgan et al. 2012) guide clinical dose selections, and enable data-driven clinical "Go/No Go" decisions depending on whether the onset of side effects occurs prior to or after desired target occupancy range for efficacy (Wong et al. 2009).

drug companies are now increasingly teaming up to clinically test targeted pathway inhibitor combinations.