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Brucella organisms persist intracellularly, and their DNA has been detected in the peripheral blood of asymptomatic patients, even years after the diagnosis of clinical brucellosis and its clinically successful cure.
Biomechanical stability of the new implant was intensively tested and compared to other clinically successful shaft prostheses prior to the start of the clinical study [ 32, 33].
Until now, no clinically successful therapeutic treatment or drug for AD has been reported to date.
Two of the most clinically successful and intensively studied technologies that operate at the nanoscale are "stealth" and "targeted" medicines.
In clinically successful DBS applications, such as Parkinson disease, the dosing problem can be solved by trial and error.
Even for clinically successful hip stems such as the Exeter-V40 occasional failures are reported.
However, most devices lack the stability found in clinically successful circumferential fusion constructs.
Rouillard, A. D., Hurle, M. R. & Agarwal, P. Systematic interrogation of diverse Omic data reveals interpretable, robust, and generalizable transcriptomic features of clinically successful therapeutic targets.
Rarely has an attempt to introduce biological activity into a biomaterial been clinically successful in these applications.
Results: All blocks were judged to be clinically successful based on the presence of adequate intraoperative and early postoperative analgesia.
A clinically successful stem should ideally reduce risk for stress shielding while maintaining adequate primary stability for biological fixation.
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