Sentence examples for clinically substantial from inspiring English sources

Although it remains unclear whether or not the modulating effects of cimetidine on DC function observed in our investigation in vitro have clinically substantial meanings, clinical effectiveness of cimetidine against gastrointestinal malignancies are considered to be due to the total of immunological and non-immunological actions of cimetidine.

Clinically, substantial controversy still surrounds the choice of fluid for resuscitation.

Significant intra- and inter-patient variability limited possible performance gains so that they are unlikely to be clinically substantial, indicating a need for a further increase patient-specific or sub-cohort specific approaches to manage variability.

In designing a new ORS that would reduce stool weight and diarrhea duration, we felt that it would be important for the difference to be not only statistically significant but also both quantitatively appreciable and clinically substantial.

The responsiveness was good as long as the improvement in patients' health status was clinically substantial.

We hypothesized that patients with POH and the subset cohort with POPA (POH with pulmonary infiltrate) would each have a clinically substantial occurrence rate.

This discovery is clinically significant as substantial amount of P. aeruginosa chronic infection isolates bear a loss-of-function las system (Cabrol et al., 2003; Denervaud et al., 2004; Hamood et al., 1996; Schaber et al., 2004; Smith et al., 2006).

[11], [13] Previous research has demonstrated that placebo responses in IBS are substantial and clinically significant.

Interhospital transfers are subject to clinically significant delays, and substantial travel distances.

The transfusion of allogeneic blood or blood products results in substantial and clinically significant changes in recipient immune function.

These decreases of WBC and platelet counts do not appear to be clinically significant, unlike the substantial decrease in red blood cell mass.