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In addition, patients treated with fenoldopam required fewer diuretics and vasodilators, demonstrating a clinically observable clinical benefit of fenoldopam associated with the reduction in biomarker concentrations.
At present we lack clinical data to determine whether such oscillations are clinically observable.
This difference in the inflammatory pattern enables us to generate some hypotheses: (a) in the presence of an intense SIRS, such as in trauma patients, the AOX cocktail downregulated the inflammatory response with clinically observable effects, while (b) there was no detectable biological or clinical effect in those patients with limited SIRS.
We distinguished between clinically observable superficial inflammations and histologically detectable deep infections.
The proposed model is computationally fast and uses clinically observable parameters.
It added that several workers had been "irradiated after contamination of their skin", but that no clinically observable health effects had been reported.
Similar(15)
The tolerability of TIV/AS03 was suggested by the similar incidences of unsolicited symptoms in the three groups and the lack of any clinically-observable safety concerns.
A change in Goebel-Hiller tinnitus questionnaire score of 5 points is considered clinically relevant and observable in a clinical population [ 54, 57].
At the time of diagnosis, histologically confirmed lymph node metastases were present in 5/58 (8.6%) FMC cases and no clinically and radiographically observable distant organ metastases were present.
Oral administration of silver nanoparticles of up to 32 ppm to healthy volunteers did not induce observable clinically important toxicity markers [ 7].
Based upon our clinical experience, a difference of 5 points in tinnitus score (range: 0 – 80) according to the TQ is both clinically relevant and observable in a study setting [ 34], and 0.486 is a conservative estimate of the effect size [ 15, 23, 25, 34].
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