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However, to achieve clinically desired results, this process has to be repeated multiple times and over multiple sessions.
Therefore improving the analysis of the initial seizure propagation using mathematical models is clinically desired: Identifying the spatio-temporal dependencies in ictal ECoG recordings could fulfill this task.
In addition, the simpler titration schedule may allow the patient to achieve clinically desired results more quickly than with the immediate release formulation.
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Thus, treatments are selected by forward simulation with a clinically specified desired risk of light hypoglycaemia (5% BG < 4.4 mmol/L) due to these possible future variations.
The stochastic output range is thus overlaid with a clinically specified desired control range (4.0-4.4 4.0-4.4mol/L depending on intervention interval in this case) to maximize the likelihood of being in that range.
To lower metabolic susceptibility and in turn reduce unwanted metabolic toxicity that was observed clinically, while retaining desired antibacterial activity, the use of azoles as amide bioisosteres had also been investigated.
Nutrition was 30 to 100% of clinical goal feed (max change ±30% per intervention) and constant rates were used when desired clinically.
However, in Parkinson's disease, the broad frequency-amplitude tolerance of the underlying tremor circuit suggests that its median frequency will have to be entrained to frequencies outside of this broad tolerance zone, before stimuli applied systematically at certain tremor phases can induce either tremor amplitude potentiation or, as desired clinically, amplitude suppression.
Orthodontics has been developing greatly in achieving the desired results both clinically and technically.
If these societal benefits are considered important by policy makers, then there is a case for public interventions to encourage manufacturing research in an attempt to achieve the desired goal of producing clinically usable medicines and drug delivery devices.
Nanofibrous scaffolds that are morphologically/structurally similar to natural ECM are highly interested for tissue engineering; however, the electrospinning technique has the difficulty in directly producing clinically relevant 3D nanofibrous scaffolds with desired structural properties.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com