VEGF inhibition has been the focus of considerable clinically oriented research, and angiogenesis blockade has been shown to be effective in different in vivo models of arthritis, including CIA [ 18, 20, 36, 49, 50].
From all the available ECM scaffolds, only the SIS (Oasis) and to a lesser extent Graft Jacket have been reported clinically in a considerable number of patients to improve chronic wounds without adding cells [ 3, 21, 25].
Salivary gland tumors are clinically diverse and present considerable challenges in both diagnosis and treatment.
Our findings indicate a considerable and clinically meaningful impact on visual functioning and a moderate association with vision-specific emotional well-being in PXE patients with VI, irrespective of the presence of CVCs.
Given the growing interest in identifying clinically relevant epigenetic alterations, considerable attention has been given to the polycomb group (PcG) gene family in the context of human cancer [ 20].
Clarification of the relationship between DRB1 alleles, RF, anti-CCP and disease severity remains a matter of considerable importance both clinically (prediction of disease phenotype and the design of clinical trials/studies) and because of the pathogenetic insights that may result.
An increase in extracellular fluid, if it is considerable, may be clinically apparent as edema, a swelling of the tissues by fluid, which can usually be displaced by firm pressure.
The outbreak was untypical since a considerable number of clinically diagnosed patients were adults.
There is a considerable rate of clinically relevant posttraumatic stress symptoms and significantly diminished HRQL in close family members of CCI patients following ICU stay.
