Sentence examples for clinically attainable from inspiring English sources

Even when mecA/PBP2′ was induced strongly, ceftobiprole MICs for MRSA only reached 4 mg/L, a clinically attainable concentration.

We found that Nelfinavir inhibited the growth of cervical cancer cell lines at the lowest micromolar concentrations clinically attainable.

Survival analyses revealed that mTOR inhibitors sensitized both HT-sensitive PCa and CRPC cells to IR at clinically attainable doses.

The present study has delineated two independent cytotoxic activities of L‐ASNase; that is, Asn depletion at low doses and Gln depletion at clinically attainable intermediate doses.

In conclusion, we demonstrated that clinically attainable intermediate doses of L‐ASNase target the Gln addiction phenotype in lymphoid cell lines.

As previously reported, dasatinib IC50s in vitro in CLL lymphocytes expressing wild type TP53 were not in the clinically attainable range (mean value of 30 μmol/l, Table I) (Amrein et al, 2008a).

3 To extend the understanding of L‐ASNase action in lymphoid cell lines, we compared the effects of a clinically readily attainable intermediate dose of L‐ASNase (1 U/mL) 26, 27 for three lymphoid malignant cell lines: Jurkat (T‐ALL), Jeko (mantle cell lymphoma) and Reh (pre‐B ALL).

Results provide initial evidence that CAT and CAI can improve children's attention in the classroom - and support additional studies to determine whether more clinically significant benefits are attainable.

Collectively, these sources suggest that an attainable and clinically meaningful effect size would be 0.50, which translates into a difference between mean changes of 1 unit (absolute).

A more attainable goal would be to reduce clinically active trachoma to some threshold, below which scarring and blindness would never occur or at least would become so rare that trachoma would no longer be a major public health concern (2 ).

We hypothesized that TMA profiling of a panel of biomarkers, either proven or potentially relevant for prognostic and/or predictive assessment of breast cancer, might permit the detection of clinically relevant prognostic groups from those with four or more positive axillary lymph nodes above that attainable from conventional factors alone.