The rapid induction of apoptosis in human leukaemia cells at concentrations even lower than those that can be achieved and maintained for many hours in plasma of patients receiving the drug at tolerable dose, provides a rational to undertake clinical investigation wit this drug in human leukaemia.
The subscales "1.2 Discontinuity-relationships" (d = 2.27) and "2.1 Incoherence-consistent self image" (d = 2.56) showed the strongest discrimination, while "2.2 Incoherence-autonomy" showed the lowest discrimination between the adolescents from school and from the clinical group wit PD. * = Significance of all score differences were p < .001.001
We evaluated the hypothesis that molecular markers could be used to divide the triple-negative tumors into different subgroups wit different clinical outcome.
We thank the clinical research assistants, E. de Wit-Taen and A. Abrahams, for collecting the data of the Early Arthritis Cohort.
He was much loved and admired by his colleagues, not only for his brilliance as a clinical psychologist, but also for his quick wit, willingness to share his gifts, and dedication to his family.
Serious gaming, especially given the context of enthusiastic students, has proved to be an effective training method in domains such as medical education, for example, in clinical decision-making and patient interaction (de Wit-Zuurendonk & Oei, 2011).
Mr. Littlefield was one of those needy patients who ended up with a clinical care specialist because doctors were at their wits' end.
To wit, McWilliams' [ 5] review of the clinical and economic literature indicates that extended health insurance coverage has indeed helped improve population health across a range of outcomes.
The EORTC is implementing a phase III clinical trial to examine the effect of adjuvant treatment wit erlotinib in unselected ovarian cancer patients in remission after first line chemotherapy (EORTC protocol 55041).
Simplifying the recommendations of the guidelines into a format of a protocol, or a clinical pathway, overcomes a known barrier for implementation of evidence and wit, the complexity of some guidelines [ 23].
During multiple cycles, 6% of patients had an adverse event related to aprepitant, 19% had serious clinical adverse events, and 12% discontinued treatment, a comparable pattern to that seen with standard antiemetic treatment (de Wit et al. 2004).
