Hypersensitivity can be clinically visible or "silent," when the drug activity decreases without clinical symptoms [ 8– 12].
These results suggest that making expert clinical thinking visible is a potentially valuable approach for assisting to bridge the gap between expert and novice reasoning [ 10, 14, 68].
In 2010, the FDA approved a 3.75% imiquimod formulation for treatment of clinical typical, visible, or palpable actinic keratoses on the face or balding scalp.
In conclusion, this original study allowed observing and demonstrating not only the clinical and visible immediate results but also the internal mechanisms of the skin through an external, noninvasive, and painless stimulation.
The resulting PORRT form documents 11 risk factors for ECC in three domains: behavioral and environmental factors (oral hygiene, diet, sleeping practices, fluoride use, and family dental problems), clinical factors (visible plaque, non-carious enamel defects, non-cavitated [white spot] carious lesions, cavitated carious lesions) and special health care needs.
"A visible, clinical metastasis — the kind that we can detect with CAT scans or MRIs — must only occur once a dormant cell has been reactivated and begins to divide," he said.
Also, the apex thickening, often seen in clinical images, is visible in the IQ-SPECT data.
The vP129/swIL1β infected pigs did not show visible clinical signs, while respiratory distress and lethargy were evident in pigs infected with the parental virus.
Considering that major clinical benefits are visible in the long term and that our results are difficult to collate due to the fact that MDS is an orphan disease, the clinical experts agreed on the reasonableness of our findings.
