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Ongoing clinical trials explore T cell receptor (TCR) gene therapy as a treatment option for cancer, but responses in solid tumors are hampered by the immunosuppressive microenvironment.
We sought to review the outcomes of recent clinical trials, explore the design of the interventions and to discuss the methodological approaches and issues that arise when investigating a complex mix of interventions in order to guide future research.
We sought to review the outcomes of recent clinical trials, explore the structure of the interventions and also to discuss the methodological approaches and issues that arise when investigating a complex mix of interventions in order to guide future research.
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