We sought to define normative visual field (VF) values for children using common clinical test protocols for kinetic and static perimetry.
This level of detail is not described in existing NICE guidelines [ 4, 15], and there appears to be no national or international consensus regarding the optimal clinical testing protocol.
Our lab has strong collaborations with surgeons and interventionalists from local hospitals for constant input into the device design process and to enable accurate development of clinically representative laboratory and pre-clinical test protocols.
After generating T cells against cytomegalovirus, medical biotechnologist Erica Dander, 26, wrote in collaboration with her multi-disciplinary team a successful clinical trial protocol to test whether injecting the T cells could kill infected cells in transplant patients.
The long examination protocol comprised a physical and neurological assessment, which included assessment of behaviour, cranial nerve function, proprioception, locomotion in a corridor, muscle movements and signs of pruritus, such as hair loss and scratch response testing, similar to the clinical examination protocol used for sheep [ 12] (see additional file 2: Long exam protocol).
As for all clinical trials, the details of the objectives, patient eligibility, treatment schedules, endpoints and all tests should be documented in the clinical trial protocol.
The clinical examination protocol included complete ocular examination with standard ophthalmologic tests, cerebral computed tomography (CT) or magnetic resonance imaging (MRI) of the brain, and standard neurological examination.
This study tested the concurrent validity of a modified shortened clinical examination protocol for occupational health surveillance, called the HECO protocol, compared to the original protocol developed by Ohlsson et al. (1994).
Plasma was analysed to quantify levels of blood metabolites including non-esterified fatty acids (NEFA) [Randox Laboratories, Belfast, Northern Ireland], β-hydroxybutyrate (BHB) [Randox Laboratories, Belfast, Northern Ireland], glucose and urea (Audit Diagnostics, Cork, Ireland) and was performed on Beckman Coulter AU 400 clinical analyser using test protocol supplied by the manufacturer.
Understand the clinical trial protocol.
