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More recently, the discrepancy between induction of TAA-specific immune responses and clinical responsiveness has also been attributed to CTL defects.
In these studies, we observed that pre-treatment expression of mIL1R2 mRNA by PBMC in response to dexamethasone stimulation in vitro, correlated with clinical responsiveness to oral steroid therapy.
Clinical responsiveness to cognitive behavioural therapy for psychosis (CBTp) varies.
T-VEC also appears to substantially enhance clinical responsiveness to checkpoint inhibitor antibody therapy.
Individual differences in clinical responsiveness to antiepileptic drugs are due to a complex interaction between environmental factors and genetic variation.
This B cell lymphoproliferative disorder has shown clinical responsiveness not only to generalized immunotherapy and cytotoxic chemotherapy, but also to inhibitors of herpesvirus DNA replication, consistent with the involvement of lytic phase of replication.
Additionally, there are currently no established means to predict clinical responsiveness to therapy.
This data is also consistent with our observed correlation between relative genotype age and clinical responsiveness.
Similar(3)
The diagnosis of this rare phenomenon, characterized by cephalic pain, with or without migrainous features, relies on the EEG evidence of an irrefutable ictal pattern and on the electro-clinical responsiveness to intravenous antiepileptic drugs [2, 3].
If we set a threshold for clinical steroid responsiveness to be a greater than 500 fold induction of mIL1R2 in vitro, then the sensitivity of this test is 100% with a confidence interval of 71.7 to 100%.
When choosing a treatment success variable to be used in a clinical trial, responsiveness is one of the key properties.
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