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This finding has potential clinical ramifications given the application of 18q loss of heterozygosity events as a potential indicator for adjuvant treatment in stage II colorectal carcinoma.
The design of a new therapy to treat and/or prevent P-Ec, based on successful use of TAFIa inhibitors, may have significant clinical ramifications.
This review highlights the important mechanistic underpinnings and clinical ramifications of OIH and discusses future research directions and the latest clinical evidence for modulation of this potentially troublesome clinical phenomenon.
As the weight of the evidence correlating ITH to poor prognosis burgeons, it has become increasingly important to determine the mechanisms by which a tumor acquires ITH, find clinically-adaptable means to quantify ITH and design strategies to deal with the numerous profound clinical ramifications that ITH forces upon us.
If further research shows that the injectable spheres trigger new capillary growth, they could have "immense clinical ramifications," says Elazer Edelman, director of the Harvard-MIT BiomediCambridge, Massachusettsn Cambridge, Massachusetts.
All clinical ramifications of infection occur during the asexual blood-stage of infection.
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The immediate clinical ramification is that anti-TNF therapy must be more cautiously applied and monitored.
The immediate clinical ramification is that anti-TNF therapeutics must be more cautiously applied and monitored, especially in patients with compromised cardiac function45,46.
The immediate clinical ramification would be that anti-TNF therapy must be more cautiously applied and monitored, since it could possess an unappreciated capability to modulate TPR and hence, haemodynamic parameters.
Finally, while induced bronchoconstriction by bronchial challenge is only a diagnostic and research tool for asthma, we offer a speculation about the potential clinical ramification of our observations.
Nikolic, S. B., Abhayaratna, W. P., Leano, R., Stowasser, M. & Sharman, J. E. Waiting a few extra minutes before measuring blood pressure has potentially important clinical and research ramifications.
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