The new DSM-V diagnostic criteria on sleep wake disorder have chosen to use broad criteria to increase reliability in clinical diagnosis, making specific operationalizations for use in research more challenging.
In secondary analyses, we will assess the reliability and validity of clinical subtypes and an alternative operationalization of the likelihood of CTE (i.e., probable CTE vs. possible or no CTE).
The aim of this systematic literature review was to evaluate according to six criteria the operationalization of relapse in RCTs of clinical innovations for the prevention of relapse in first-episode psychosis.
While there are well-established frameworks that serve to inform the pursuit of basic science, clinical, and translational research in support of the operationalization of the personalized healthcare paradigm, equivalent constructs that may enable biomedical informatics innovation and practice aligned with such objectives are noticeably sparse.
We present a roadmap (Figure1) to integrate actual genetic knowledge into the Electronic Patient Record and into clinical research in Family medicine, which would enable urgent operationalization of readily available knowledge feasible in daily genetic medical care.
Future research should continue to test different operationalizations of the dental home concept, evaluate clinical outcomes associated with dental homes, and identify the specific features of dental homes that lead to good oral health.
This could make urgent operationalization of readily available genetic knowledge feasible in clinical research and consequently improved medical care.
To determine whether the International Classification of Functioning, Disability and Health ICFF) categories relevant to spinal cord injury (SCI) can be integrated in clinical measures and to obtain insights to guide their future operationalization.
After outlining the septic shock illness concept, this article evaluates how bedside operationalization of current definitions of septic shock definitions and their corresponding clinical criteria influence the validity, reliability, and feasibility attributes [ 2].
Problems may be encountered; however, with consistency in the operationalization of "important secondary outcomes" since this term is not currently part of the standard clinical trial lexicon.
