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In light of this conflict between clinical necessity and study purity, estimates of the size of the association between exposure to sick poultry and H5N1 infection could be interpreted as maximums that are likely to have been inflated by this selection bias.
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Given this evidence gap and clinical necessity, it is likely that clinical trials in the near future will be designed and implemented to address these issues.
On the other hand, multiple informants as in our study are often a clinical necessity, but from a research point of view this more complex and sometimes contradictory information may weaken the agreement between raters.
Through this collection of papers, we hope to highlight areas of uncertainty, recent advances, and future clinical necessity.
This analysis was based on four indicators: (1) primary clinical necessity, (2) clinical effectiveness, (3) adverse effect, and (4) competitive price.
Commission E determines safety and effectiveness from published historical and chemical data, clinical, animal and experimental studies.
Who work with intellectually disabled children and study clinical psychology.
These pre-clinical results support a future clinical validation study in larger and broader cohorts.
To study the necessity and ability to climb stairs in persons after a lower-limb amputation (LLA) and the relation of this ability with personal and clinical variables.
There is an absolute necessity for more clinical studies and data.
Field investigation is a necessity to study land subsidence consequences and damages.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com