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As a consequence of the smaller difference between active treatment and placebo treatment, larger patient samples and/or more sensitive clinical methods are needed to detect differences between drug and placebo.
Experimental, longitudinal or clinical methods are needed to illuminate these processes.
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This is highly important, because predictive pre-clinical methods are needed to improve the high attrition rate of drug candidates during clinical testing.
In the absence of clinical trial data, other methods are needed to establish evidence-based processes of care for this common clinical scenario.
This study focuses on the evaluation of existing automated text de-identification methods and tools, as applied to Veterans Health Administration VHAA) clinical documents, to assess which methods perform better with each category of PHI found in our clinical notes; and when new methods are needed to improve performance.
Thus, more efficient and less costly methods are needed in clinical diagnostics.
Although this is reasonable in the research setting, false-negative test results in the clinical setting are of little benefit and methods are needed to improve the sensitivity and specificity of WGS for clinical diagnosis.
The presence and severity of dysplasia in OPMLs is associated with poorer clinical outcomes 2, 3, but more rigorous methods are needed to predict the malignant potential of oral lesions as rates of malignant progression from oral dysplasia vary greatly 4. Tumors often contain hierarchical arrangements of genetically or epigenetically dissimilar tumorigenic and non tumorigenic cells 5– 7.
New methods are needed to translate more commonly available clinical process measures into potential impact on clinical outcomes.
24 New methods are needed to gain insight into hand proprioception in both normal and clinical populations.
Obviously, stronger methods are needed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com