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Terminology such as "sub-clinical", "latent", and "minimal" appear to trivialize the disease and have been replaced by the term covert.
Based on the clinical information, latent or active TB was excluded from the controls.
Moreover, the localization of the bacteria in particular organs suggests the possibility of transmission through sexual intercourse and may ensure the prevalence of both clinical and latent infections.
The preferential location of the TSPY-transgene product in the hyperplastic stromal cells was somewhat different from our previous observations in clinical and latent prostate cancer specimens, in which the TSPY protein were mostly localized in the epithelial tumor cells [ 27, 28].
This is mainly motivated by the belief that early symptoms of the disease (cancer in this case) in the sub-clinical phase (latent period) might induce or contra-indicate the use of NSAIDs (protopathic bias) [ 44, 67].
Perinatal hypoxia ischaemia affects cognitive outcomes of infants even when clinical symptoms were latent and intensive care was not required.
The individual asthma and wheezing forms as defined by clinical classification or latent class analysis also have a strong genetic component (except for transient wheezing).
In the absence of a gold standard for the clinical observations, a latent class analysis (LCA) evaluating the true within-herd lameness prevalence was used.
Seven centers of the Barcelona Tuberculosis Research Unit (BTRU) (Unitat d'Investigació en Tuberculosi de Barcelona) are collaborating with the Division of Tuberculosis Elimination of the United States Centers for Disease Control and Prevention in a series of clinical trials on latent tuberculosis infection and tuberculosis disease.
As outlined above stress- and sleep related increased prolactin levels appear to inhibit corpus luteum function and to reduce the secretion of progesterone in the luteal phase of the menstrual cycle [22] and this has led to clinical studies in latent hyperprolactinemic women with premenstrual mastodynia (Fig. 2).
Further, about 50% of monkeys show clinical characteristics of latent TB [11].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com