Exact(11)
Clinical extent was used if no pathologic stage was available.
An inverse relationship was seen between survival rates and clinical extent of disease.
The clinical extent of disease at presentation was based on TNM group staging (UICC 1978).
Marzano et al 13 recently published a therapeutic algorithm based on the clinical extent of the lesions.
No high-quality data from prospective trials are available; nevertheless, locoregional therapy decisions should be based on both pretreatment and the clinical extent of disease.
The clinical extent of invasive disease caused by S. pneumoniae is severe; sequelae and case-fatality rates are almost 4× higher in native than in nonnative populations (1, 4 ).
Similar(49)
Covariates were: centrally reviewed Gleason grade, baseline PSA value, clinical stage, extent of disease (proportion of positive cores), age at diagnosis, and initial hormone management.
Covariates evaluated were centrally reviewed Gleason score, baseline PSA value, clinical stage, extent of disease (proportion of positive chips), age at diagnosis and Ki-67 score (% cells positive).
Covariates included centrally reviewed Gleason score, baseline PSA value, clinical stage, extent of cancer (proportion of positive cores), age at diagnosis, and Ki-67.
Covariates evaluated were: centrally reviewed Gleason primary grade and score, baseline PSA value, clinical stage, extent of disease (proportion of positive cores), age at diagnosis, Ki-67 immunohistochemistry, and initial treatment (no initial treatment or early hormone management).
In contrast, other pre-clinical and, to some extent, clinical data suggest that GC induce resistance to chemo- and radio-therapy and increase metastatic potential [ 40].
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