As a young doctor in the 1980s, in the early days of the Aids epidemic, Lange led research on the clinical evolution of HIV infection and in the 90s was instrumental in the development of antiretroviral therapy.
Demographic datas, empirical and definitive antibiotic therapy (ET and DT), clinical evolution, and outcome were recorded.
For 3 images, the prognostic evaluation agreed with the real clinical evolution.
We analyzed whether the evolution of these variables would predict clinical evolution and outcome.
It was based on clinical, biological, chest X-ray and echocardiography data and on clinical evolution.
Multiple sclerosis (MS) is a chronic neurodegenerative disease with unknown etiology and variable clinical evolution.
Evaluation and adjustment if any- of antimicrobial treatment before 72 h, according to bacteriological results and clinical evolution, were recorded.
There is increasing evidence that persistent microcirculatory alterations are related to clinical evolution independently from macrohemodynamic improvement [4 8].
There is increasing evidence that microcirculatory alterations might persist independently from macrohemodynamic improvement and are related to clinical evolution.
Furthermore, similar StO2 evolution patterns have been noticed for all treated patients, regardless of their clinical evolution.
The magnitude of endotoxemia, the high risk criteria and correlation with clinical evolution vary widely between studies.
