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Up to 40% of patients may be excluded from research despite there being little clinical doubt about the diagnosis.
If there is clinical doubt further investigations including MRI and biopsy should be performed.
In the case of unequivocal findings or clinical doubt, additional MRI is requested.
The reasons for this included clinical doubt (33%), limited decision time (32%) and assessment error (25%) [ 15].
After recruitment if there was clinical doubt that the cancer remained in remission, all data on that subject were excluded from analysis.
Follow-up visits were anticipated in the presence of a clinical doubt of recurrence or on the basis of patients' requests.
Similar(49)
Given the clinical doubts that arousal could be well palliated, the family must convince the team that the benefits thereof outweigh the detriments.
EBM requires four steps: a) formulating a clinical question arising from a doubt concerning a patient; b) conducting an efficient literature search to answer this question; c) applying rules of evidence to selected articles to determine the validity of their design and the clinical relevance of their results; and d) applying these results in the patient who was the stimulus for the question.
I am oversimplifying, of course, but even I find the reasoning superficially compelling, despite the fact that it is effectively suggesting I should be out of a job (I deal with patients, but since I am not doing anything clinical I doubt I am really what most people have in mind when they talk about front-line staff).Unfortunately, though, things don't tend to be quite so cut-and-dried.
Increasingly, both in academic and clinical circles, doubts about "brain death" are being voiced.
While past studies suggest that patient education may be associated with better clinical outcomes, doubts remain about the effectiveness of patient education strategies [ 10- 12].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com