Sentence examples for clinical development candidate from inspiring English sources
ASP8370 was selected as a clinical development candidate with significant ameliorative effects on neuropathic pain.
Terms such as "nondruggable GPCRs" describe a unique group of GPCRs having strong biological hypothesis validation, but for which medicinal chemistry efforts based on orthosteric ligands have failed to produce marketed drugs (or even clinical development candidates).
This comparative analysis validates the design of bapineuzumab and attests to the robustness of antibody humanization technology as a platform for obtaining clinical development candidates from preclinical leads for disease therapy in humans.
CHMI data inform the decision for or against further clinical development of candidate vaccines, including whether to test in a pediatric population.
Continued progress in the development of such T-cell therapies will require the identification of the relevant biomarker strategies to support and guide clinical development of the candidate products.
Such a shift in the protective threshold would also suggest that the 50% protection threshold was achieved by the 20 µg dose group in our Phase I. Overall, these results are reassuring for the continued clinical development of this candidate H5 VLP vaccine.
Its clinical development and product candidates are small-molecule enzyme inhibitors designed to target key biochemical pathways involved in human diseases with critical unmet needs.
Hence there is need for technologies to address various issues in preclinical and clinical development of drug candidates which lead to attrition.
"The drug market is still dominated by small molecules and more than 80% of the clinical development of drug candidates in the top 20 pharmaceutical firms is still based on small molecules.
Three scenarios exist: 1, drug approved for use in adults; 2, drug candidate in phase I or phase II of clinical development; and 3, drug candidate for pediatric use only.
