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Clinical data are lacking to guide the management of HMPV pneumonias.
Narrowing of the small arterioles has been hypothesized to contribute to the pathogenesis of hypertension, but prospective clinical data are lacking.
Comparisons in animal models have not demonstrated a clear advantage of one technique over the other, but clinical data are lacking.
Despite the uncertainties and knowledge gaps related to parameters influencing drugs bioavailability in each clinical condition, PBPK models provide a valuable support for prospective dose recommendations and efficacy/safety assessment in special populations when consistent clinical data are lacking.
Clinical data are lacking to support the use of the tapered tracheal cuff to prevent microaspiration in critically ill patient.
Despite the promising research that has been conducted using multimodality inputs [28] and in distinguishing Parkinsonian subtypes [29], rigorous tests on a range of realistic clinical data are lacking.
Similar(36)
In adults information on the relationship between imaging and clinical data is lacking.
However, a 2006 2007 study in Artibonite Valley, Haiti, showed the chloroquine resistance associated Pfcrt76T genotype in ≈6% (5/79) of P. falciparum isolates, although clinical data were lacking (10 ).
Of the 36 cases with known follow-up remaining, 35 were alive with disease and 1 was dead for other causes; since the follow-up was not long enough we pooled them with the 35 cases for which clinical data were lacking.
Although subjective patient satisfaction is high in many of the studies with skin fillers and skin thickness as measured using wrinkle scale ratings of appearance, long-term efficacy and clinical safety data are lacking because patients are likely to continue to undergo subsequent cosmetic interventions.
In retrospective and small prospective studies, off-label bevacizumab appears to have similar efficacy to ranibizumab, but a head-to-head trial of efficacy and safety has not yet been conducted, and rigorous clinical trial data are lacking in general for off-label bevacizumab in neovascular AMD (Raftery et al. 2007).
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CEO of Professional Science Editing for Scientists @ prosciediting.com