Sentence examples for clinical compound from inspiring English sources

Analogues of the clinical compound MGCD0103 (A) were designed and synthesized.

The leading compound 53 was as potent as the clinical compound LGK974 in a cell based STF reporter gene assay.

The straight triphenyl linked compound 11a showed similar anti-HCV activity to the clinical compound BMS-790052 and a superior cytotoxicity profile in three different cell lines, with an EC50 value of 26 pM and a therapeutic index of over four million in an HCV replicon assay.

The focus of this study was to identify key proteins and pathways required for the clinical compound I-BET762 to induce tumor cell killing.

Moreover, it could be argued that a clinical compound measure including the feet such as the DAS44 would have been more suitable for comparison with the new HaF-score.

Docetaxel (Taxotere®, Aventis Laboratories, France) was extemporaneously prepared according to the procedure used for the clinical compound, and injected intraperitoneally (i.p). at a dose of 20 mg kg−1 every 3 weeks, as already published (Oudard et al, 2003).

Like all clinical compounds, Gardasil has been extensively tested for years, constantly monitored for potential adverse effects.

Therefore, pharmacological inhibition of YAP/TAZ might be achieved through already available FDA-approved clinical compounds or combinations therewith.

Thus our study provides proof-of-concept evidence that clinical compounds identified through promoting cell reprogramming efficiency could be applied safely to facilitate tissue regeneration.

Thus our study offers proof-of-concept evidence that cocktail of clinical compounds improving cell reprogramming favors tissue recovery after acute damages, which is an attractive strategy for regenerative purpose.

Many of the selection assays are similar to those used for discovery of clinical compounds, although the distribution and clearance of target specific radioligands requires different in vitro and in vivo methods and new derivatives.