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We conducted a systematic search of eight journals, Annals of Internal Medicine, BMJ, Circulation, Clinical Infectious Diseases (CID), JAMA, the Journal of Clinical Oncology (JCO), Lancet and the New England Journal of Medicine (NEJM), to identify RCTs reporting the use of interim analysis with or without specification of a DMC, between June 2000 and June 2005.
Taken together, the clinical parameters for circulation were similar in both patient groups.
In the central venous catheter-guided treatment, clinical assessment of circulation was explicitly included with the central venous pressure, blood pressure and urine output to guide the treatment.
The quantitative marker, the highest serum tobramycin concentration, was used for correlation with clinical markers of circulation and organ failure at the same day and with markers on ICU admission day.
Early response in clinical settings includes: circulation of national guidelines on clinical management of dengue; staff training including officers in public and private hospitals; engagement of the private sector; establishment of dengue treatment areas in major hospitals and in high risk districts.
Eligible papers for this reproducibility study were studies on diagnostic accuracy published in 2000 in one of the following 12 journals: Annals of Internal Medicine, Archives of Internal Medicine, Archives of Neurology, BMJ, Circulation, Clinical Chemistry, Gut, JAMA, Lancet, New England Journal of Medicine, Neurology, Radiology.
Apart from routine clinical measurements of circulation, gas exchange, fluid balance, renal and hepatic function, severity of illness was scored using the Acute Physiology and Chronic Health Evaluation (APACHE II, III and IV) systems [ 8, 9] over the first 24-hours of ICU admission.
Therefore, this study confirmed that adequate density of PCL sheath in PGS grafts could initiate stable and high-quality muscular remodeling, which contributes to long-term success in arterial circulation before clinical translation.
