The ability to detect and monitor potential toxicities of new clinical candidates is an absolute necessity for any pharmaceutical agent before the clinic.
OSI will acquire Gilead's clinical candidates in oncology, the study of tumors, and all related intellectual property, as well as its operations in Boulder, Colo., including clinical research and drug development personnel, infrastructure and plants.
The dual inhibitory action may result in poor clinical candidates.
When choosing clinical candidates, what is the optimum affinity for a mAb?
About 72%% of 189 clinical candidates were correctly identified by the proposed workflow.
These results suggest that 16-membered azalides could be promising compounds as clinical candidates.
Many benzofuran containing synthetic drugs and clinical candidates have been derived from natural products.
These findings offer opportunities for development of safe clinical candidates against tuberculosis.
Over the past decade there has been a literal explosion of novel bispecific antibody technologies, approaches, and clinical candidates.
The study identified two orally active metalloporphyrins and one injectable metalloporphyrin as clinical candidates for further development in PD.
Rohitukine is a medicinally important natural product which has inspired the discovery of two anticancer clinical candidates.
