Sentence examples for clinical agent from inspiring English sources

As the mechanisms implicated in cisplatin-induced AKI are still unclear, an effective clinical agent for preventing cisplatin-induced AKI is needed.

This liposomal formulation could potentially produce a viable clinical agent for improving the anticancer activity of Rg3.

Representing the first example of an antibody drug conjugate (ADC), calicheamicin γ1I was introduced as a clinical agent marketed by American Home Products under the name of Mylotarg for the treatment of leukemia.

Therefore an agent incorporating 5-HT re-uptake inhibition coupled with 5-HT1A and/or 5-HT1B antagonismor antagonismayay provide a fast acting clinical agent.

The average r1 relaxivities of the of the surface bound complexes (obtained at 9.4 T and 25 °C) are 10.7 and 9.7 s−1 mM−1, respectively, as compared to 4.7 s−1 mM−1 for the clinical agent MagnevistTM.

Their broad-spectrum chemotherapeutic potential has been assessed at 24- and 96-h intervals, along with that of the clinical agent cisplatin, using breast (MCF-7), prostate (DU145), colon (HT29), and intrinsically cisplatin-resistant ovarian (SK-OV-3) human cancer cells. 1 represents a potent cytotoxic agent with IC50 values ranging from 5.6 to 3.4 μM across all cell lines, including SK-OV-3.

Amphotericin B, calicheamicin γ1I, rapamycin, taxol, the epothilones, and vancomycin are all clinical agents.

Gold nanoparticles (AuNPs) have recently attracted attention as clinical agents for enhancing the effect of radiotherapy in various cancers.

This review will discuss the discovery of these different classes, as well as their development as potential clinical agents.

Animal models are increasingly gaining values by cross-comparisons of response or resistance to clinical agents used for patients.

Most HSP90 inhibitors and all clinical agents bind competitively and potently to the N-terminal ATPase pocket.