Exact(1)
However, expressing FL- clu or CLUH using da GAL4 rescued the egg-laying ability of females (Fig. 1L), as well as their ability to climb (supplementary material Fig. S1B).
Similar(59)
In the '70s and '80s, visionary climbers like Reinhold Messner, the first man to climb Everest solo and without supplementary oxygen, would both extend the limits of Alpine-style climbing in the Himalayas (traveling up the mountain quickly, in a small group with minimal gear) and establish the prototype of the professional climber-celebrity.
We therefore investigated whether Aβ43 could modulate Aβ42 toxicity by comparing the effect of Aβ42+Aβ43 with that of Aβ42+Aβ42 on climbing ability and survival of flies (supplementary Fig. 5).
There was a decline in climbing rod performance with age (p < 0.0001, Mann Whitney test; supplementary data Fig. 2A), but we found no difference in climbing rod performance between 21 month old mice that passed or failed the static rod test (supplementary data Fig. 2B).
During the intervention period, signs were placed right above the elevator buttons stating 'Stair climbing increases energy expenditure 11-fold' (see online supplementary appendix figure 1).
There was no difference observed in the climbing ability of the transgenic control siblings (P Kruskal Wallis=0.493) (supplementary material Fig. S3, Table S4).
Gliders can sometimes climb in these waves to great altitudes, although pilots must use supplementary oxygen to avoid hypoxia.
Additionally, γ irradiated mice also showed increased time required climbing the barrier relative to controls (p<0.02 compared to control; Supplementary figure 1B).
The Europeans, accompanied by a photographer recording their attempt to climb the 8,848-metre 8,848-metret) mountain by a new "undisclosed" route without supplementary oxygen, ignored the request and carried on, the eyewitness said.
We could observe a rather modest but yet significant reduction of toxicity in the combined Aβ42+Aβ43 line both in terms of climbing (** p < 0.01, induced-Aβ42+Aβ43 vs. induced-Aβ42+Aβ42 induced-Aβ42+Aβ42upplementary Fig. 5a) and survival (p < 0.0001, induced-Aβ42+Aβ43 vs. induced-Aβ42+Aβ42, log-rank test, supplementANOVAig. 5b).
Additionally, decreased brain volume in MRI and increased time required to climb the physical barrier after radiation exposure provided further evidence linking premature senescence and radiation (Supplementary figure 1A and B).
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