Sentence examples for cleft it from inspiring English sources

Given the location of residue Met at the end of the latter α-helix, pointing its side chain towards the interior of the cleft, it is conceivable that it might control the solvent accessibility of haem III and, concomitantly, regulate its reduction potential value.

While several lines of evidence suggest a specific role on the part of glial α2 Na+/K+ pump in active reuptake of glutamate from the synaptic cleft, it is plausible that CSD facilitation in the FHM2 mouse model is sustained by inefficient glutamate clearance by astrocytes, leading to an increase in cortical excitatory neurotransmission [106].

For optimal management of the oral cleft, it is imperative that CPO is diagnosed as early as possible.

However, given that residues in the AST can form direct interactions with ligands in the active site cleft, it also likely contributes to the specificity and affinity of some inhibitors.

Sulfenic acid at the site of the cysteine is unlikely itself to physically block ATP entry into the cleft; it seems more likely that cysteine oxidation will perturb the surrounding residues, which in turn may alter residues necessary for ATP positioning or hydrolysis, leading to decreased ATPase activity.

Since all candidate genes in this study were chosen a priori for their potential roles in facial clefting, it is important to separate true associations from spurious ones.

Given these considerations, because the HT clearly drives protein accumulation in Maurer's clefts, it must accomplish this as a lumenal signal that sorts protein into these secretory clefts.

Further studies revealed that agrin is synthesized by motor neurons that release it into the synaptic cleft where it stably integrates into the synaptic basal lamina (BL), a specialized thin layer of the extracellular matrix (ECM) [3] [5].

This will cause more dopamine to be left in the synaptic cleft, where it has its effect.

If we feel called upon to invent something to help children with cleft palates, it will be because having a cleft palate is bad, not because it is unjust.

And Freddie Fox makes some amazing noises as a youngster possessed of a palate that may not be quite as cleft as it would at first appear.