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Central Europe, cleft from the West during the cold war, is the continent's universal joint: a fact that puts the responsibility for surmounting the politics of historical division squarely on the shoulders of a united Germany.
Our structure also reveals that the inhibitor approaches the active-site cleft from the opposite side of the crossover loop as compared to the direction of approach of ubiquitin's C-terminal tail, thereby occupying the P1′ (leaving group) site, a binding site perhaps used by the unknown C-terminal extension of ubiquitin in the actual in vivo substrate(s) of UCHL1.
They took out the cleft from my chin and the shadows under my cheeks," pouts Heidi Klum.
Intra-articular contrast application may help to differentiate re-tears (where the contrast is leaking into the cleft) from healing (where granulation and scar tissue fills up the cleft and where the contrast has no space to leak in).
Physiologically, a pyramidal neuron (resp. an interneuron) releases glutamate (resp. GABA) in the synaptic cleft from where it binds to receptors on the postsynaptic neuron, which stands for the main mechanism of synaptic transmission.
According to this hypothesis, the newly synthesized messenger travels across the synaptic cleft from the postsynaptic to the presynaptic cell, leading to a chain of events that facilitate the presynaptic response to subsequent stimuli.
Similar(43)
HIG is a member of the immunoglobulin superfamily that is transported and secreted to synaptic clefts from the early stage of pupal synaptogenesis.
Thus, data of cases with syndromic orofacial clefts from large population-based studies are infrequent.
A number of patients with orofacial clefts from Kagera and Kigoma were refugees, or born to refugees, from Burundi and the Democratic Republic of Congo.
The controls in the study sample include 220,113 individuals without oral clefts from a randomly selected sample of about 5% of the total population of births in Denmark each year from 1936 to 2002.
The study employs unique secondary population-based data from several administrative inpatient, civil registration, demographic and labor market databases for 7,670 individuals born with oral clefts between 1936 and 2002 in Denmark, and 220,113 individuals without oral clefts from a 5% random sample of the total birth population from 1936 to 2002.
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