Sentence examples for cleavage to prevent from inspiring English sources

Samples were introduced into the fluid cell immediately after cleavage to prevent contamination.

Akt also may control FoxO proteins activity and subsequently block caspase cleavage to prevent the induction of apoptotic cell death.

In previous reports, codon-optimized HA ectodomain with mutated cleavage site (to prevent processing of HA1-HA2) and addeddexogenousous foldon sequence at the C-terminus was expressed transiently in 293 cells in order to produce stable oligomers [3], [4], [5].

To overcome the fusogenic cytotoxicity of JEV prM-E protein expression in mammalian cell lines, Konishi et al. [ 33] introduced a mutation at the prM/M cleavage site to prevent authentic processing and to reduce the toxic fusion activity of the expressed VLP, and established an F-cell line using CHO-k1 as the parent cell line.

In the current study, we have used FasL-deficient mice as well as mice from a gene-targeted line in which the FasL metalloproteinase cleavage sites were mutated to prevent cleavage of the membrane-bound protein.

These studies indicate the importance of Bid cleavage by caspase-8 as the initial step in the protein degradation, and the protection from caspase cleavage could be expected to prevent Bid degradation.

The SK COOH-terminal Lys414 residue and residues Arg253 Leu260 in the SK β-domain were deleted to prevent cleavage by plasmin (Pm) and to disable Pg substrate binding to the SK·Pg∗/Pm catalytic complexes, respectively.

To prevent cleavage of the anchoring segment and increase the long-term stability of zwitterionic polymer-based brushes in seawater, Vancso and co-workers investigate diblock copolymer-type brushes composed of bottom hydrophobic segments and a polysulfobetaine top on the substrate of SiOx (Fig. 9) [74].

As increased transformation efficiency using unmethylated DNA is rare [28], the foreign genetic materials should be methylated prior to delivery to prevent cleavage by the RM systems.

We cannot rule out that the mutations that were made to prevent cleavage at subsequent processing sites had some influence on the differences observed between oxidation of endogenous and versus exogenous protease.

The γ-secretase inhibitor DAPT was used to prevent cleavage and functional activation of Notch [ 30].