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The term 'spiral cleavage' reflects a characteristic spatial pattern of cell division exhibited most conspicuously from the third through fifth cell cycles.
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Because all events after target cleavage reflect activities available in cells for double-strand break repair, different systems will have different properties with respect to these parameters.
The cleavage percentages reflect the decrease in the integral area of the full-length 18-mer RNA substrate peak.
Any damage to neurons due to apoE4-specific cleavage would reflect a toxic gain of function of the protein.
It is also possible that, as STAT3 activity is needed for the self-renewal of murine ES cells [ 38], cleavage might reflect a low level of differentiation among the ES cells.
We conclude that the fluorescence loss reflects cleavage of the APP construct C-terminal to the pHluorin tag and subsequent loss into the extracellular medium; in a perfused cell culture system, such as ours, secreted molecules or peptides will be removed in milliseconds from the synaptic cleft.
When a Chi sequence is present, a prominent band appears in the smear of cleavage products, which reflects the downregulation of nuclease activity on the 3′-terminated strand and the protection of that strand between Chi and the distal DNA end.
This initial processing event is followed by successive tripeptide generation, which proceeds from the ε-cleavage site to the γ-cleavage sites and reflects the periodicity of the α-helix.
But as he struggles to put a more contemporary veneer on his rule, he faces a society still suffering deep cleavages that reflect unresolved questions of identity.
The peak at +1 reflects cleavages due to the same H4 molecule on the same side of the dyad, while the peak at +7 reflects cleavages due to adjacent H4 molecules across the nucleosome dyad.
Thus, the evaluation of LC3-I cleavage into LC3-II reflects the activation of autophagy [ 36].
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