We characterized the extended cleavage pattern and provide corresponding IceLogos.
Depending on their cleavage pattern chitinases can be divided in endochitinases and exochitinases.
Aggrecanases are the main enzymes responsible for aggrecan degradation, due to their specific cleavage pattern.
Compound 10 also exhibited an in vitro DNA cleavage pattern similar to that of GL-331 (5).
Thus, agarases can be classified into α-agarases (EC 3.2.1.158), β-agarases (EC 3.2.1.81), and β-porphyranases (EC 3.2.1.178) according to the cleavage pattern (Chi et al. 2012).
Type II REases are widely used in genetic technologies because of their stable cleavage pattern and are the most well studied.
Pore-filling carbonate cements generally show a rhombic crystal structure with a prominent cleavage pattern and tend to infill the pore space completely where present (Fig. 8a).
Platinum-containing camptothecins produced platinum-DNA adducts and topoisomerase I-mediated DNA damage with cleavage pattern and persistence similar to SN38, the active principle of irinotecan.
Regarding the cleavage pattern on polysaccharides, the release of oligosaccharides with a wide degree of polymerization indicated a characteristic of endoglucanase activity.
The DNA cleavage pattern of AZP scFokI suggests that the enhanced dsDNA cleavage was due to increased formation of FokI dimer in AZP scFokI.
Our newly designed nucleases, Sp1(P1)GLI and Sp1(P1G)GLI, can strongly bind to a lanthanide ion and show a unique DNA cleavage pattern, in which certain positions between the two DNA-binding sites are specifically cleaved.
