Sentence examples for cleavage effect from inspiring English sources

Here, an endogenous long non-coding RNA (IPS1, Induced by Phosphate Starvation1) binds to miR399 but the pairing is interrupted by a mismatched loop at the expected miRNA cleavage site, which abolishes the cleavage effect (Franco-Zorrilla et al. 2007).

The device consists of 2 sensing platforms (both are interdigitated array microelectrodes – IDAMs) within 1 common fluidic chamber: one detects the cell morphology responses via Electric Cell-substrate ImpECISce Sensing (ECIS) technique, meanwhile the other records the cleavage effect between cell-secreted MMP-9 and the surface immobilized peptide via the capacitance-based sensing method.

To further evaluate the mode of Vpr-induced cell killing in neuroblastoma cells (whether or not Vpr kills those cells by apoptosis or other mechanism) potential caspase-3 cleavage effect was measured as an indication of apoptosis.

Our present work also demonstrates that heparin and HS hinder the in vitro plasmid cleavage effect of TpT.

Ethylenediamine and trans--cyclohexane-1,2-diamine showed the most prominent cleavage effects.

The pore diameter is difficult to assess because of cleavage effects, but it was estimated between 5 and 10 nm, thus confirming the expected mesoporous nanostructure.

In this study, b and y ion fragmentation patterns and residue-specific cleavage effects in HCD mode were statistically characterized on a LTQ Orbitrap Velos mass spectrometer.

Although caspases and calpains are reported to account for the majority of cleavage effects on polyQ expanded disease proteins, several fragmentation events could not be explained by their proteolytic activity.

To evaluate photochemical-cleavage effects, three 2-nitrobenzyl-modified C-HOMedA analogues were synthesized and separated into single diastereomers, dA.III.a (α-isopropyl), dA.III.b (α-isopropyl-4-OMe), and dA.III.c (α-isopropyl-6-NO2), along with the parent dA.I (see the Supporting Information).

Myoblasts deficient in p110α or p110α and p110β together showed increased Caspase-3 and PARP cleavage, an effect fully reversed by IGF-I.

Given that the 10H10 antibody mainly targets TF/FVIIa signalling by inhibition of protease-activated receptor 2 (PAR-2) cleavage, the effect of TF/FVIIa on GSIS is likely to be mediated via a PAR-2-dependent pathway [ 33].