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Notably, Ulp1 cleavage clearly showed that the majority of HMW-SUMO species did not enter the gel and accumulated on the well bottom.
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Altogether, our data show that internal cleavage was clearly symmetric at the palindromic LTR-LTR junction.
SNAP-25 cleavage was clearly detected 1 day and 1 week after the BoNT/E injection (Fig. 1).
Trask cleavage is clearly not required for its phosphorylation since the uncleaved wildtype Trask and the cleavage-resistant M10 Trask mutant readily undergo tyrosine phosphorylation.
However, we could not detect LC3 conversion in CEM cells after Dex treatment when caspase-3 cleavage was clearly observed.
poly (ADP-ribose) polymerase (PARP) and caspase-7 cleavage were clearly more pronounced in PC3 cells treated with PEITC and anti-Fas in combination, followed by cells treated with PEITC alone and then by cells treated with anti-Fas alone.
Following FASL treatment, partial PARP cleavage was clearly detected only for the two primary cell lines, while a slight reduction of the full-length protein (p32) indicated caspase-3 activation.
However, PARP cleavage was clearly evident in A2780 cells and together with the fact that zVAD-fmk strongly suppressed DOX-induced apoptosis, we postulate that other yet unconfirmed mechanisms of caspase-dependent apoptosis are activated, such as the extrinsic pathway and caspase-8.
As mentioned before, PARP-cleavage is clearly induced by UV-B-irradiation.
The spatiotemporal geometry of cleavage in mollusks clearly has the potential to contain a great deal of information, but for the most part we do not know its developmental significance.
The coarse compositional bias in the mRNA cleavage region is clearly conserved between both species, pointing to a functional conservation of mRNA cleavage and possibly a participation of several observed regions in the cleavage process.
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