Sentence examples for cleavage based on from inspiring English sources

The Drosophila protein has two potential sites for S1 cleavage, based on analysis of the primary amino-acid sequence.

To clarify the process of VEGF release, we develop a molecular-detailed quantitative model of VEGF cleavage based on an endothelial tip cell cleaving and releasing nearby VEGF.

In the first digestion step (step 7), the linkage between the first and second disaccharides on the chain is assigned a probability of cleavage based on the specificity of the particular lyase [30], [37] [42] (Figure 1 and Materials and Methods).

The mutation could affect normal signal peptide cleavage based on its proximity to the cleavage site and the nature of the changed amino acid.

The classical method is based on electrophoretic separation of cleaved substrates on SDS-PAGE, using Atg8 substrates fused with a tag C-terminal to the cleavage site.,, The fused tag allows the detection of cleavage based on either the change of the size of the substrate or the appearance of the C-terminal cleavage products.

Research has suggested a long-term decline in turnout at national elections in western democracies since the 1970s; it seems most likely that this is a consequence of partisan dealignment (i.e., a weakening of partisan identification), the erosion of social cleavages based on class and religion, and increasing voter discontent.

While ethnicity contributed much to political instability in Fiji the existence of additional cleavages based on class, kinship and centre-periphery dichotomy created a multi-layered picture.

The potential cleavage sites of prohormones that can result in bioactive neuropeptides were predicted and compared to the cleavages based on known neuropeptide sequences.

The original study which defined S1 cleavage was based on the human Notch2 receptor and established that this cleavage is sensitive to Brefeldin A and led to the suggestion that this cleavage is necessary for the receptor to reach the cell surface [12].

Interestingly cobalt, but not magnesium, calcium or manganese, supported cleavage of the topoisomerase IIβ enzyme using a metal affinity cleavage assay based on Fenton chemistry [42] (unpublished data).

To overcome this difficulty, we incorporated tryptic peptides preceding the cleavage sites based on predicted signal sequences from SMART [ 27], SignalP4.0 [ 28], and cleavage sites annotated in HPRD [ 29] into our analysis pipeline.